Description:
Pirazinamida is secondary in vitro antituberculosis pirazinamida under acidic active against mycobacteria. Bakterisid is mainly on the results of intracellular tuberculosis. In oral administration pirazinamida easily absorbed and scattered widely throughout the body tissues. Peak serum levels achieved in less than 2 hours and half-life between 10-16 hours. Pirazinamida suffered hydrolysis and hydroxylation into pirazinoat hydroxy acid which is the main metabolites and excreted through glomerular filtration.
Composition:
Each tablet contains 500 mg pirazinamida.
Indication:
Treatment of tuberculosis (as tuberkulostatik secondary) are given together with other tuberkulostatik.
Dose:
20-30 mg / kg BW / day in single or divided doses (maximum 2 grams / day).
Packaging:
CEC 100

May 25th, 2010
Obat Penyakit